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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCN10A All Species: 5.45
Human Site: T1044 Identified Species: 13.33
UniProt: Q9Y5Y9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5Y9 NP_006505.2 1956 220626 T1044 E R C G D H L T P R S P G T G
Chimpanzee Pan troglodytes XP_516372 1956 220469 T1044 E R C G D H L T P R S P G T G
Rhesus Macaque Macaca mulatta XP_001100281 1957 223189 D1065 P I A V G E S D F E N L N T E
Dog Lupus familis XP_858252 1960 223552 D1065 P I A V G E S D F E N L N T E
Cat Felis silvestris
Mouse Mus musculus Q6QIY3 1958 220533 A1045 Q K C E D H Q A A R S P P S G
Rat Rattus norvegicus Q62968 1956 219714 A1045 Q K C E N H Q A A R S P A S M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232818 2040 231951 G1122 D Q R C Q S P G A R S Q N S E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q20JQ7 1784 201644 D947 I R R C P C L D L D V S Q G K
Tiger Blowfish Takifugu rubipres Q2XVR7 1892 213080 T969 D D V D S E V T C E E N E H H
Fruit Fly Dros. melanogaster P35500 2131 239344 L1178 K P K K S K Y L N N A T D D D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 57.5 57.5 N.A. 82.2 83 N.A. N.A. 62.5 N.A. 54 54.1 43.1 N.A. N.A. N.A.
Protein Similarity: 100 99.6 72.9 72.5 N.A. 89.2 89.8 N.A. N.A. 75.1 N.A. 68.7 69.1 58.6 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 6.6 N.A. 46.6 33.3 N.A. N.A. 13.3 N.A. 13.3 6.6 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 13.3 N.A. 66.6 60 N.A. N.A. 33.3 N.A. 13.3 20 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 0 0 0 0 20 30 0 10 0 10 0 0 % A
% Cys: 0 0 40 20 0 10 0 0 10 0 0 0 0 0 0 % C
% Asp: 20 10 0 10 30 0 0 30 0 10 0 0 10 10 10 % D
% Glu: 20 0 0 20 0 30 0 0 0 30 10 0 10 0 30 % E
% Phe: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % F
% Gly: 0 0 0 20 20 0 0 10 0 0 0 0 20 10 30 % G
% His: 0 0 0 0 0 40 0 0 0 0 0 0 0 10 10 % H
% Ile: 10 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 20 10 10 0 10 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 0 0 0 0 30 10 10 0 0 20 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 10 0 0 0 10 10 20 10 30 0 0 % N
% Pro: 20 10 0 0 10 0 10 0 20 0 0 40 10 0 0 % P
% Gln: 20 10 0 0 10 0 20 0 0 0 0 10 10 0 0 % Q
% Arg: 0 30 20 0 0 0 0 0 0 50 0 0 0 0 0 % R
% Ser: 0 0 0 0 20 10 20 0 0 0 50 10 0 30 0 % S
% Thr: 0 0 0 0 0 0 0 30 0 0 0 10 0 40 0 % T
% Val: 0 0 10 20 0 0 10 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _